The original antigenic sin: When the body first encounters an infection it produces effective antibodies against its dominant antigens and thus eliminates the infection. But when it encounters the same infection, at a later evolved stage, with a new dominant antigen, with the original antigen now being recessive, the immune system will still produce the former antibodies against this old “now recessive antigen” and not develop new antibodies against the new dominant one, this results in the production of ineffective antibodies and thus a weak immunity.
